Testosterone Propionate is a single ester testosterone compound and represents one of the most important testosterone compounds every manufactured. When synthetic testosterone was first created it was in its pure form. Simply put there was no ester attached, thereby providing a fast acting compound that would necessarily require a very frequent administration schedule. In 1937 the pharmaceutical giant Schering out of Germany would release the first ester base testosterone in Testosterone Propionate under the trade name Testoviron. The same trade name it would eventually give to its Testosterone Enanthate product. By attaching the Propionate ester to the hormone, this would allow for the hormone’s release time to be controlled and provided a more efficient means in maintaining stable blood levels. Although this was not the first synthetic testosterone preparation created, Testosterone Propionate would become the first commercially available testosterone product. It would also dominate the medical community until the 1960’s and much of the newly born performance enhancing community.
 
 
During the 1960’s Testosterone Propionate would lose a lot of its popularity in favor of the larger ester base Testosterone Cypionate and Testosterone Enanthate compounds. However, it is still used medicinally today as well as by many performance athletes. You will find more of it among the latter group than anywhere else. Many performance enhancing athletes actually believe the Propionate form will lead to less water retention than the dominating large ester forms of Testosterone. For this reason, it is often the preferred form of testosterone during cutting cycles. While this is the common belief it is also a misconception. Regardless of the testosterone form the hormone does not become active in the body until the ester detaches and then the hormone is released. Regardless of the ester originally attached to the hormone you still have the same testosterone hormone in the body once the ester is removed. So where does this myth come from? Common sense tells us that when running a cutting cycle the individual will consume a calorie restricted diet, one that is often healthier and with less of an abundance in carbohydrates. As a result the individual will hold less water. Then we have the fact that many often use less testosterone when dieting and if your total dose is less than an off-season dose there’s less active hormone available to promote water retention. All in all, you can receive the same benefits with Testosterone Propionate as all testosterone forms. However, an advantage of Testosterone Propionate is that it can be easier to maintain stable and peaked blood levels of the hormone due to the very frequent injection protocol compared to large ester bases.
 
Outside of performance enhancement, Testosterone Propionate has found a number of therapeutic uses. However, like all testosterone forms the treatment of male androgen deficiency such as low testosterone has always been the most common point of use. Testosterone Propionate has, however, also found other points of interesting use over the years in treating menopausal issues, chronic cystic mastitis, excessive lactation and endometriosis. This was for a decent amount of time the most commonly used testosterone for female medical treatment, but it has largely been removed from U.S. FDA approval in female patients. It is still approved for male use in the U.S. but it will be found in medicinal circles more commonly in other parts of the world. However, Cypionate and Enanthate remain the dominate forms worldwide leaving Propionate to be primarily use in performance circles.
 

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