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CAS 841205-47-8 Pharmaceutical Raw Materials SARMS Raw Powder Ibutamoren MK-677

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CAS 841205-47-8 Pharmaceutical Raw Materials SARMS Raw Powder Ibutamoren MK-677

China CAS 841205-47-8 Pharmaceutical Raw Materials SARMS Raw Powder Ibutamoren MK-677 supplier
CAS 841205-47-8 Pharmaceutical Raw Materials SARMS Raw Powder Ibutamoren MK-677 supplier CAS 841205-47-8 Pharmaceutical Raw Materials SARMS Raw Powder Ibutamoren MK-677 supplier CAS 841205-47-8 Pharmaceutical Raw Materials SARMS Raw Powder Ibutamoren MK-677 supplier

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Product Details:

Place of Origin: Hubei, China
Brand Name: Mking
Certification: ISO9001, SGS
Model Number: CAS 841205-47-8

Payment & Shipping Terms:

Minimum Order Quantity: 10 Grams
Price: Negotiate
Packaging Details: As you required
Delivery Time: Within 24hours
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 100 Kg per Month
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Detailed Product Description
Product Name: MK-677 CAS: 841205-47-8
Assay: 99.6% Policy: Reshipping Policy
Packing: As You Required Delivery: 5-7 Working Days
Shipment: EMS, HKEMS, DHL, FEDEX, EUB Description: Yellow Powder

CAS 841205-47-8 SARMS Raw Powder Ibutamoren MK-677 For Muscle Enhancement


Basic Info


Synonyms: Ibutamoren;2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide;IbutaMoren (MK-677)

CAS No.: 159634-47-6
Molecular formula: C27H36N4O5S
Molecular Weight: 528.67

 

Abstract

 

MK-677 is an selective agonist of the gherlin receptor and a growth hormone secretagogue stimulating the growth hormone. Studies have shown to sustain activation of GH-IGF-1, increase in lean body mass and bone mineral density.

 

MK-677 is so great because it increases growth hormone levels but doesn’t increase in other hormones such as cortisol.

 

Ibutamoren is frequently discussed on online forums for its muscle-building properties. It is available over the counter and used by those wishing to increase their growth hormone levels.

 

However, clinical studies of this compound are relatively few. In the text below, we will highlight what is known about ibutamoren so far.

 

Ibutamoren (also known as ibutamoren mesylate or MK-677), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1) [R, R].

 

Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.

 

GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition [R]. Therefore, we can expect that ibutamoren may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren has on appetite – and as expected, like ghrelin, ibutamoren increases it.

 

A great thing about ibutamoren is that it increases growth hormone levels with little or no increase in other hormones, such as cortisol [R, R]. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

 

Application

 

An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARd agonist.

 

Usage An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.

 

 

SARM
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48 RAD140 CAS: 118237-47-0
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50 YK11 CAS: 431579-34-9

 

CAS 841205-47-8 Pharmaceutical Raw Materials SARMS Raw Powder Ibutamoren MK-677

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