Payment & Shipping Terms:
|Appearance:||White Powder||Assay:||99% Min|
|Type:||Raw Sarms Powder||Grade:||Medicine Grade|
|Package:||Discreet Or As Required||Application:||Increase Energy|
|Express:||EMS, DHL, FedEx, Or As Required||Delivery:||7 Days, Door To Door|
Bodybuilding Supplement Pharmaceutical Raw Materials SR9011 Sarm Powder
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic.
Why Do We Need to Use SARM ?
In general, SARMs offer three key benefits - increased muscle mass, decreased fat mass, and increased bone mass.
SARM aren't just designed and meant for athletes; as previously discussed there are a slew of populations that could benefit from SARMs.
Those with one or more of the following conditions could benefit from SARMs: muscle wasting disorders (such as : sarcopenia, amyotrophic lateral sclerosis, and cystic fibrosis), sports injuries, burn injuries, weakness and/or body wasting due to cancer or HIV, and frailty and/or muscle atrophy as a result of the aging process.
Although there are many drugs designed to improve the health of these populations, SARMs also have the unique benefit of being non-methylated and non-aromatized by the body, so they're not toxic to the liver nor do they convert in to other active androgen or estrogen compounds. Liver toxicity and aromatization is a very serious concern when using pro-hormones and AASs. As you can see, SARMs benefit both chronically ill individuals as well healthy individuals looking to maximize quality of life.
Furthermore, SARM have demonstrated the ability to minimize or prevent muscle trophy when muscles were immobilized in casts. This is great news for athletes who work hard on the field and in the weight room to build muscle mass, strength, and power as SARM may positively impact the recovery process.
SR9011 Packaging Details
1-5kg Aluminium Foiled Bag and Ziplock Bag
Packed with Aluminium Foiled Bag with ZIplock Bag inside .
25kg Paper Drum
Packed with Paper drum with Double Plastic Bags inside
SR9011 Related Hot Sale SARM
Andarine S-4 / GTx-007 CAS: 401900-40-1
Ostarine / MK-2866 / GTx-024 CAS: 841205-47-8
Ligandrol / LGD-4033 CAS: 1165910-22-4
Cardarine / GW-501516 CAS: 317318-70-0
RAD140 CAS: 118237-47-0
YK11 CAS: 431579-34-9
MK-677 / IBUTAMORIN CAS: 159752-10-0
SR9009 CAS: 1379686-30-2
SR9011 CAS: 1379686-29-9
Why Choose Us ?
1. Quality: we deal with relevant products for many years, and have many stable customers from all over the world.
2. Package: Discreet package, 99% pass customs clearance.
3. Delivery: No matter where you are, about 7 working days to arrive.
4. Guarantee: Reship if stop by customs, the more you buy, the more discounts you will enjoy.